Brain corticotropin-releasing hormone (CRH) circuits in the developing rat: Effect of maternal deprivation
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چکیده
منابع مشابه
Characterization of corticotropin-releasing hormone (CRH) in human skin.
We have confirmed the expression of CRH and CRH receptor type 1 genes in human skin, cultured HaCaT keratinocytes, squamous cell carcinoma, and melanoma cells. The size of CRH messenger ribonucleic acid (mRNA), estimated by Northern blot hybridization, was 1.5 kilobases. CRH peptide was identified by reverse phase high pressure liquid chromatography separation in both whole skin and cultured ce...
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Corticotropin-releasing hormone (CRH) mediates responses to a variety of stressors. We subjected rats to a one hour period of an acute stressor, physical restraint, and determined the impact on subsequent sleep-wake behavior. Restraint at the beginning of the light period, but not the dark period, increased waking and reduced rapid eye movements sleep (REMS) without dramatically altering slow w...
متن کاملChanges in hippocampal theta following intrahippocampal corticotropin-releasing hormone (CRH) infusions in the rat.
Hippocampal theta activity is a large amplitude, sinusoidal wave that occurs during attentive immobility and exploratory behaviour in the rat, and it is thought to be involved in memory formation. Recent reports suggest that corticotropin-releasing hormone (CRH) has pro-mnemonic effects in rodents. Because memory-enhancing substances/manipulations generally alter either theta frequencies or amp...
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OBJECTIVES: Corticotropin-releasing hormone (CRH) and leptin (LEP) are two neuropeptides involved in the regulation of food intake, energy homeostasis and stress response. These neuropeptides play an important role in the regulation of the hypothalamo-pituitary-gonadal (HPG) axis, too. It is known that leptin can affect the synthesis and release of CRH in the hypothalamus. There is no informati...
متن کاملRapid induction of corticotropin-releasing hormone gene transcription in the paraventricular nucleus of the developing rat.
Neonates from postnatal days (pnd) 4-14 display a minimal pituitary-adrenal response to mild stress, the so-called stress hyporesponsive period (SHRP). However, during the SHRP, maternal deprivation (deprived) alters the pituitary-adrenal system, enabling neonates to become endocrine responsive to specific stimuli. Although neonates do display stress-induced ACTH, there is limited evidence for ...
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ژورنال
عنوان ژورنال: Brain Research
سال: 2006
ISSN: 0006-8993
DOI: 10.1016/j.brainres.2006.08.104